The Museum of popular arts and traditions of the Upper Tiber Valley is located in the historic Palazzo Taglieschi. Here you can find paintings, wooden sculptures, sacred and domestic furniture from the Medieval period to the 18th century. Of particular interest are works by Jacopo della Quercia, Jacopo Vignali, and Giovanni della Robbia, as well as a still functioning 16th-century organ.
This museum was set up here because of the by now famous culture of this town, which is only a few kilometres from Sansepolcro and to which it is connected by a straight road (from the 14th century) that crosses the Tiber plain.
Important weekly markets for wool were held in Anghiari in the past and along with them, woollen mills, dye-works and hat makers sprang up. In addition, craftsmen and weapon makers arrived and the inlay work, engraving, repoussé work, and damascening from the area became famous far and wide as works of art, making Anghiari so well known that the Museum of popular arts and traditions of the Upper Tiber Valley was set up in the Palazzo Taglieschi